Tretizen 20


Manufacturer: Zenlabs Pharmaceuticals Inc
Category: PCT
Substance: Isotretinoin
Package: 20mg 10 pills


Tretizen 20 (Isotretinoin) belongs to a class of drugs called retinoids, which are synthetic derivatives of vitamin A. These drugs are used to treat severe acne and other skin conditions. Topical isotretinoin has been shown to be effective as a treatment in combination with other medications for oral lichen planus. Because isotretinoin is derived from vitamin A, users of this drug should be careful to avoid vitamin A supplements, as this can cause dangerous side effects.

Increased heart rate, headache, visual disturbances, malaise, nervousness, dry lips, dry skin, hair abnormalities, skin peeling, increased susceptibility of sunburn, itching, nausea, fatigue, suicidal ideation.

  • Notify your doctor if you are pregnant, are allergic to parabens, vitamin A, or other retinoids, have diabetes mellitus, increased triglyceride levels, or pancreatitis.
  • Not for use during pregnancy. Requires two negative pregnancy tests; effective contraceptive used at least one month prior to starting therapy, during therapy, and for at least one month after discontinuing therapy, and prescriptions can only be written for one month supply at a time.
  • Not to be used if you are a woman in childbearing age unless complying with effective contraceptive methods, and patients must commit to using two forms of birth control.
    Patients must be enrolled in the manufacturer sponsored and FDA approved monitoring programs.
  • Depression, psychosis, aggressive or violent behavior, and rarely suicidal thoughts and actions have been reported during use.
  • Patients who order Accutane need to understand that it use only for severe cystic acne that have not responded to less toxic drugs.
  • Avoid excessive exposure to the wind, sun or cold temperatures. Retinoids may increase your skin’s vulnerability to these conditions and may cause dryness and burning.
  • Using this medication may make it difficult to wear contact lens because of the drying effect on the eyes.

This drug has a black box warning describing the known teratogenic effects when taken during pregnancy. In addition, it describes the restricted dispensing program that requires signed patient consent and counseling along with negative pregnancy tests prior to the initiation of therapy. Additional information is also provided regarding the risk of suicidal ideation. Read the complete patient brochure and discuss these risks with your doctor.